Lamotrigine Side Effects

Lamotrigine side effects are:

  • A lack of coordination or balance

  • Vision with both eyes

  • Eyesight is hazy

  • Movement of the eyes that is out of control

  • Thinking or focusing is difficult

  • The difficulty of articulating oneself

  • Headache

  • Drowsiness

  • Dizziness

  • Diarrhoea

  • Constipation

  • A decrease in hunger

  • Loss of weight

  • Heartburn

  • Nausea

  • Vomiting

  • A lack of taste in the tongue

  • Back, stomach, or joint discomfort

  • Menstruation cycles that are irregular or uncomfortable

  • Vaginal discomfort, swelling, or irritation

  • A section of the body shakes uncontrollably

Lamotrigine side effects

Side Effects of Lamotrigine

Some adverse effects may be associated with Lamotrigine. If any of the following symptoms persist or worsen, contact your doctor:

Common Side Effects

Severe expressions are shared if they have been experienced.

These have a Less Severe appearance if you’ve had any experience with them.

  • An Infectious Disease

  • Doubly Perceived

  • Difficulty Seeing

  • A burning sensation at the back of the throat

  • A Runny Nose and Stuffy Throat

  • Mouth Sore

  • Backache

  • Drowsiness

  • Dizziness

  • Inability to Sleep

  • Low Effort

  • Myofascial Shock

  • Headache

  • Pain in the chest

  • Acute Abdominal Pain with Vomiting

Infrequent Side Effects

Severe expressions are shared if they have been experienced.

  • Bleeding

  • Changes in a person’s mental state

  • Irritability

  • An Unintentional Damage

These have a Less Severe appearance if you’ve had any experience with them.

  • Mood swings

  • A Shift in Perspective

  • Eye Movements That Aren’t Consciously Controlled

  • Indigestion

  • Constipation

  • Vaginal Inflammation or Infection

  • Women’s Period Pain

  • Pain in the Joints

  • Backache

  • Pain

  • Reduced Hunger

  • Mood Sweeps Weight Loss Diarrhea

Rare Side Effects

Severe expressions are shared if they have been experienced.

  • Viruses and bacteria are not the cause of meningitis

  • A chest tumour

  • Resistance to Infection Is Decreased.

  • Hemolytic Anemia Is A Blood Disorder in Which Red Blood Cells Burst

  • Pancytopenia is a blood disorder characterized by a decrease in all blood cells.

  • Insufficiency of Blood Cells as a Result of Marrow Failure

  • Anaemia

  • Reduced Platelets in the Blood

  • Granulocytes, a kind of white blood cell, are in low concentrations.

  • White Blood Cell Deficiency

  • Neutrophils, a specific kind of white blood cell, are in low concentrations.

  • Increased Blood Eosinophils

  • A Deficiency in Blood

  • Self-Injurious Behaviour

  • Depression and Suicidal Feelings

  • Seizures That Recur Frequently, With Intervals of Unconsciousness

  • Uveitis, or inflammation of the eye’s uvea

  • Loss of Hearing

  • Diabetic Hypertension

  • On an EKG, the ST segment shifts in and out.

  • Another kind of irregular heartbeat is ventricle arrhythmia.

  • Blood Vessel Inflammation

  • Orthostatic hypotension is a kind of hypotension.

  • Oesophagal Inflammation

  • Bleeding from the Large Intestine Due to Inflammation

  • Anaemia of the Small and Large Intestines

  • Interstitial Nephritis Is One Type Of Kidney Inflammation.

  • Irritable Bowel Syndrome

  • Testicular Epididymis Inflammation

  • An Allergic Reaction to Something

  • An Allergic Skin Reaction Called Erythema Multiforme

  • Toxic Epidermal Necrolysis Is A Skin Disorder That Causes Blistering And Peeling.

  • Stevens-Johnson Syndrome, a Blistering and Peeling Skin Disorder,

  • Sloughing Skin Rash

  • Syndrome Resembling Lupus in Symptomatology

  • Rhabdomyolysis is the medical term for a condition in which muscle tissue breaks down.

  • Dyskinesia is a kind of abnormal movement disorder.

  • Bilirubin Levels Are Extremely High.

  • Pin-point sized reddish-purple spots on the skin

  • Tongue Inflammation

  • Apnea is a condition in which breathing is disrupted.

  • Abnormalities in Tests of Liver Function

  • Angioedema Is One Type Of Allergic Reaction.

  • A Drug-Induced Hypersensitivity Reaction

  • Myocardial Intraventricular Conduction Defect

  • Alcohol Absorption Problems

  • An Immune Disorder Called Hypogammaglobulinemia Is Often Found.

  • Pancreatitis

  • Failure of several different body systems

  • DRESS Syndrome is a kind of severe allergic skin reaction.

  • Hyperactive Immune Cells in the Body, Known as Hemophageal Lymphohistiocytosis.

  • Absolute Red Cell Aplasia

  • There Is A Decrease In The Levels Of Alanine And Aspartate In The Bloodstream.

These have a Less Severe appearance if you’ve had any experience with them.

  • A Goiter (slang for a goiter)

  • Anxiety Illness

  • Emotional Abuse

  • Hostility Moods

  • Anxiety-Induced Excitation

  • The Slump

  • Light Sensitivity in the Eyes

  • As the upper eyelids droop

  • Irritation of the Eyes

  • Anxiety-Inducing Earache

  • Pain in the Ear

  • Skin Bruising and Inflammation

  • An increase in blood flow.

  • Swelling And Inflammation Of The Sinus Tissue

  • a gum infection

  • Swelling and Sores in the Mouth, a Condition Called Stomatitis.

  • Sores in the Mouth

  • Tongue Pain, Redness, or Swelling

  • An Inflammation Of The Stomach Membrane Known As Gastritis

  • Bladder Inflammatory Disease

  • Production of mother milk that is not linked to the birth feeding of the baby

  • A rash or redness of the mucous membranes or the skin

  • Itching

  • Loss of Hair

  • Human hair growth in areas of the body typically lacking hair is known as hirsutism.

  • Acne

  • A Change in the Color of the Skin

  • The Skin’s Pigmentation Is Reduced.

  • Arthritis

  • Bursitis - Inflammation Of The Joint’s Encircling Sac -

  • Weakness in the Muscles

  • Cramps in the thighs

  • Loss of Recollection

  • Hallucinations

  • Fainting

  • The Inability to Rest Properly at Night

  • Chills

  • A twitch in the muscles

  • Taste Deterioration

  • Parasmia, a Misunderstood Perception Of Smell

  • Redness Of The Face And Neck For A Short Time

  • An Increase in Appetite

  • Dysarthria is a Speech Disorder

  • Heart pounding or throbbing

  • Nodes of the Lymph nodes swollen

  • Inhaling and exhaling in rapid succession

  • Yawning

  • Hiccups

  • Having a hard time putting food down

  • Burping

  • Urinary Incontinence or Pain

  • Failure to Empty the Bladder Completely

  • Urinary Incidents at Night

  • Blood Sugar Levels Are Unacceptably High

  • Pins and Needles on the Skin

  • It’s known as Urinary Instability or the sudden need to pee.

  • Weakness Across the Board

  • Malaise is a general sense of unease.

  • Maculopapular Rash Is A Skin Rash With Bumpy Areas.

  • Problems with Oral Excitement

  • Myofibril Depletion

  • Tasteless Hot Flashes and a Fast Heartbeat Due to Drug-Induced Hot Flashes


Lamotrigine has been linked to ataxia, rash, headache, sleeplessness, and nausea. Side effects include infection, dyspepsia, sleepiness and altered gait. Some lamotrigine side effects need no medical care. These adverse effects may subside as your body responds to the medication. Your doctor may also be able to help you avoid or decrease some of these adverse effects.

dealing with side effects

How to Deal with Lamotrigine’s Adverse Effects?

Side Effects Dealing with Side Effects
Headaches Rest and hydrate. Don’t overdo it on the Ask your pharmacist for a pain reliever. A week-long or severe headache should be reported to your doctor.
tired, sleepy, or dizzy These symptoms should subside as your body adapts to Lamotrigine. So don’t drive, cycle, or use equipment until you’re awake. Then your doctor may lower or gradually raise your dosage if they don’t go away. Are you not working? See your doctor. You may need to change medications.
Aggressiveness or a state of agitation Consult with your physician.
tremors or shaking If this bothers you, see your doctor. These symptoms may indicate an overdose. Try different dosages or times of the day.
a problem with sleep Your doctor should be consulted.
Diarrhoea Avoid dehydration by drinking plenty of water or squash. Less urine or black, strong-smelling pee are signs of dehydration. Take no additional diarrhoea drugs without consulting a pharmacist or doctor. Consult a physician if symptoms worsen or linger more than a week.
having the sensation of being unwell Keep meals simple and avoid rich or spicy foods. Take Lamotrigine after a meal or snack. To prevent dehydration when unwell, drink water or squash often. Consult a physician if symptoms worsen or linger more than a week.

Precautions of Lamotrigine

To ensure that you or your kid responds well to Lamotrigine, they must see their doctor frequently. Your doctor may adjust your dosage, if required, to avoid unpleasant side effects.

If you get pregnant while using this medication, notify your doctor immediately. If you’re prescribed seizure medication, your doctor may ask you to join a pregnancy registry.

Birth control pills or other female hormone products should be postponed until you speak with your doctor about starting or stopping this medication.

While using Lamotrigine with birth control pills or other female hormonal medications, you may have odd changes in your menstrual cycle, such as breakthrough bleeding.

Alcohol and another central nervous system (CNS) depressants may have an additive impact on this medication (medicines that make you drowsy or less alert).

Antihistamines, sedatives, tranquillizers, sleeping medicine, prescription pain medication or opioids, medicine for seizures or barbiturates, muscle relaxants, and anaesthetics, including certain dental anaesthetics, are all examples of CNS depressants. The above should be checked with your doctor before taking any of them.

Lamotrigine may produce blurred vision, double vision, clumsiness, unsteadiness, dizziness, or sleepiness. It would help if you did not drive or do anything else that might be risky until you know how this medication affects you. If these side effects are troublesome, see your doctor.

A rash on the skin might be an indication of a more severe side effect. If you or your kid develops a rash, a fever, flu-like symptoms, or swollen glands, or if your seizures worsen, you should see your doctor right once.

A very uncommon and life-threatening condition in which the body produces an abnormally high number of immune cells, hemophagocytic lymphohistiocytosis, may be brought on by this medication (macrophages and lymphocytes). If you’re worried about anything, make an appointment with your doctor right away.

A variety of organs in the body may be affected by severe allergic responses to Lamotrigine (e.g., liver or kidney). A fever, black urine, hives, muscular pain or stiffness, stomach discomfort or unusual exhaustion are all signs that you or your kid may be suffering from an illness.


Some individuals may get anxious, angry, or demonstrate other odd behaviours while taking this drug. Some persons may also develop suicidal thoughts and impulses or become more depressed due to this treatment.

You must notify the appropriate medical professional immediately if you or your kid experience any of the above-mentioned adverse effects.

Immediately seek medical attention if you or your kid develop a stiff neck, sleepiness or a heightened sensitivity to light. Aseptic meningitis, which is very uncommon, might be the cause of these symptoms.

If you have blurred vision, trouble reading, or any other change in vision due to therapy, contact your doctor straight once. Your doctor may request an ophthalmologist to examine your eyes (eye doctor).

Do not discontinue taking Lamotrigine without consulting with your doctor. If you abruptly stop using this medication, your seizures may recur or occur more often. Before you stop taking your medication, your doctor may want you to lessen the dosage gradually.

Make sure you talk to your doctor before taking any additional medications. Herbal and vitamin supplements and medications with or without a prescription (over-the-counter [OTC]) fall under this category.

Frequently Asked Questions

Here are some FAQs related to the side effects of Lamotrigine:

1. When using Lamotrigine, what is the most prevalent adverse effect?

Lamotrigine’s most frequent adverse effects are rashes on the skin and headaches. Lamotrigine might take up to six weeks to have an effect. During this period, you may continue to suffer fits or seizures or feel down.

2. What is Lamotrigine’s effect on the body?

An antidepressant medicine, Lamotrigine, has a direct effect on the brain. It has been licensed to treat bipolar illness (sometimes called manic depression) and certain seizure disorders. Depression and mania are symptoms of bipolar illness.

3. Is Lamotrigine making you feel any different?

When using Lamotrigine for the first time, you may experience drowsiness or sleepiness. It may also make it harder for you to get to sleep. Ask your doctor or pharmacist for advice if these symptoms persist for an extended period or if this is difficult for you.

4. Lamotrigine affects the brain in what ways?

The dopamine and serotonin receptors in the brain, for example, are mildly inhibited by Lamictal’s binding. Suppression of these receptors may lower seizure activity by “tuning down” the brain’s signals.

5. Is Lamotrigine a weight-gaining medication?

There is a little probability of gaining weight. Weight loss is more likely to occur with the usage of Lamotrigine (Lamictal). Weight gain might also occur as a result of this treatment. Heaviness is another prevalent adverse effect of this medicine.

6. Lamotrigine: Does it damage memory?

Lamotrigine seems to enhance working memory and verbal memory in people with Parkinson’s disease and stabilize their moods.

7. When taking Lamotrigine, what happens if you consume alcohol?

Taking lamoTRIgine with alcohol might cause dizziness, sleepiness, and difficulties focusing, which are all adverse effects of the drug. Thinking and judgment may also be impaired in certain persons. While using lamoTRIgine, you should avoid or restrict your use of alcohol.

8. Is Lamotrigine a risk factor for hair loss?

Toxic epidermal necrolysis, which often results in baldness, is one of the drug’s most significant side effects. Even though lamotrigine medication has been linked to epidermal necrolysis, hair loss isn’t frequently related to it in the literature.

9. How happy will I be if I take Lamotrigine?

Dr Aiken claims that Lamotrigine is the only mood stabilizer that works by elevating depression rather than reducing mania. This is an excellent option for those with bipolar disorder, where depressive symptoms often outnumber manic ones.

10. Can Lamotrigine have side effects if used in excess?

If you don’t take it precisely as directed, there are hazards. Suppose you abruptly stop taking the medication or do not take it at all. In that case, you run the risk of Stopping this medication abruptly or not taking it at all might create significant complications if you are using it to treat seizures. An increased risk of seizures is one of the side effects.


There is a chance that Lamotrigine might cause severe rashes, which may need hospitalization or even death. Valproic acid and Divalproex may increase your chance of getting a significant rash if used along with Lamotrigine. It’s also important to inform your doctor whether or not you’ve ever reacted to Lamotrigine or any other drug for epilepsy.

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