Solmux And Paracetamol - Solmux belongs to the mucolytics group. A mucolytic helps cough up phlegm (also called mucus or sputum), whereas Paracetamol is a commonly used medication that can help treat pain and reduce a high temperature (fever). Hence it belongs to the group analgesics. Research proves that there are no interactions between solmux and Paracetamol.
Indications
Solmux works by making the phlegm less thick and sticky. It can help if you have a condition that affects your lungs, including Chronic Obstructive Pulmonary Disease (COPD) and cystic fibrosis.
Taking solmux relieves some of the symptoms and makes it easier to get rid of sputum.
Paracetamol is a commonly helped to medication that can treat pain and reduce a high (fever). It is often used to relieve mild to moderate pain such as a headache, toothache or sprain, and to reduce fevers due to illnesses such as the common cold and influenza.
Paracetamol is often recommended as the first treatment for pain because it is safe for most people and side effects are rare.
Mechanism of action:
Solmux
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This medicine contains Solmux and zinc. Solmux reduces the thickness and stickiness of sputum, making it easier to cough and breathe out.
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Solmux has been shown in in vitro (in vitro) studies to significantly reduce the ability of bacteria to bind to human pharyngeal cells.
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Zinc helps upregulate the activity of cells in the immunological activity. It is a cofactor of many enzymes involved in cell division and growth.
It also acts as an antioxidant, a cofactor of the enzyme superoxide dismutase, which participates in eliminating harmful free radicals.
Paracetamol Mechanism
Paracetamol has a principal analgesic effect carried by the trigger of the descending serotonergic pathways. There are debates on its primary site of action, which may be the inhibition of prostaglandin (PG) synthesis or via an active metabolite that influences cannabinoid receptors.
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Prostaglandin H (2) synthetase (PGHS) is the enzyme that causes the metabolism of arachidonic acid to unstable PGH (2).
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The two main forms of this enzyme are constitutive PGHS-1 and inducible PGHS-2. PGHS has a cyclooxygenase (CO X) site and a peroxidase (POX) site. The conversion of arachidonic acid to PGG (2) depends on a tyrosine-385 radical at the CO X site.
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The formation of a ferryl radical cation of protoporphyrin IX from the reducing agent Fe (3+) at the POX site is essential for converting tyrosine-385 to its extreme form. Paracetamol acts as a reducing cosubstrate on the POX site and decreases the availability of the radical ferry cation protoporphyrin IX.
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Lipoxygenase enzymes can reduce its effect, generating hydroperoxides within the cell (peroxide tone) or flooding the POX site with a substrate such as PGG (2).
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The peroxide tone and excess weight explain the lack of peripheral analgesic, platelet, and anti-inflammatory effect of Paracetamol.
Summary
Alternatively, the effects of acetaminophen can be mediated by an active metabolite (p-aminophenol). P-Aminophenol is conjugated to arachidonic acid via fatty acid amide hydrolase to form AM404.
It can also work through PGHS, especially in areas of the brain with high concentrations of fatty acid amide hydrolase.
The amalgamation of Solmux and zinc provides a complementary effect on acute respiratory infections and counteracts changes in mucus viscosity and low zinc levels in respiratory diseases.
Dosage
Solmux - Adult Dosage
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Capsules: 2 capsules of 375 mg taken 3 times a day. Once symptoms improve, your doctor may recommend one 375 mg capsule four times a day.
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Syrup: 15 ml, 3 times a day. Once symptoms improve, your doctor may recommend 10 ml, to be taken 3 times a day.
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Liquid: 1 sachet taken 3 times per day, reduced to 1 sachet taken 2 times per day when symptoms improve.
Solmux - Dosage for children
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2-4 years: 1.25 ml-2.5 ml of syrup administered 4 times a day
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5-11 years: 5 ml of syrup administered 3 times a day
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12-17 years old: 15 ml of syrup administered 3 times a day
Paracetamol - Adult Dosage
Most pills for adults are one or two 500mg medicine up to 4 times in 24 hours.
Children’s dose of Paracetamol
Infant syrup: 120mg/5ml
Dosage for infant syrup (strength 120mg/5ml)
| Age | How much? | How often? |
|---|---|---|
| 3 - 6 months | 2.5ml | Maximum 4 times per day |
| 6 - 24 months | 5ml | Maximum 4 times per day |
| 2 - 4 years | 7.5ml | Maximum 4 times per day |
| 4 - 6 years | 10ml | Maximum 4 times per day |
Six plus syrup: 250mg/5ml
Dosage for six-plus syrup (strength 250mg/5ml)
| Age | How much? | How often? |
|---|---|---|
| 6 to 8 years | 5ml | Maximum 4 times in a day |
| 8 to 10 years | 7.5ml | Maximum 4 times in a day |
| 10 to 12 years | 10ml | Maximum 4 times in a day |
Tablet dosages for children
Tablet dosage for children of ages 6 to 16 years
| Age | How much? | How often? |
|---|---|---|
| 6 to 8 years | 250mg | Maximum 4 times in a day |
| 8 to 10 years | 375mg | Maximum 4 times in a day |
| 10 to 12 years | 500mg | Maximum 4 times in a day |
| 12 to 16 years | 750mg | Maximum 4 times in a day |
Always give a gap of at least 4 hours between doses.
Contraindications
Solmux Precription
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If you have had a stomach ulcer.
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Those who are pregnant or lactating mothers.
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If you are taking other medicines. It includes pills you can buy without a prescription, herbal medicines, and supplements.
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If you have had an allergic response to any medication.
Details oF Paracetamol
Always seek advice before taking acetaminophen if:
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Have liver or kidney problems
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Have alcohol problems, such as long-term alcohol abuse.
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They have a very low weight
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You are taking other medicines (see Drug interactions below)
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Do not take it if you have ever had an allergic reaction.
Side Effects
Solmux Side Effects
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Allergic reaction
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Certain types of dermatitis (inflammation of the skin), erythema multiforme (inflammatory skin disease), and Stevens-Johnson syndrome (life-threatening skin disease).
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Gastrointestinal bleeding
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Rash or rash
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dizzying
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headache
Paracetamol Side Effects
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Allergic reaction. It can cause rashes and swelling.
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Redness, hypotension, and tachycardia can happen when acetaminophen is given into the arm’s veins in the hospital.
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Blood disorders include thrombocytopenia (low number of platelets) and leukopenia).
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Overdose (overdose) damages the liver and kidneys; It can be fatal in severe cases.
Overdose
Overdose of Solmux
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Signs and Symptoms of Overdose: Overdose of carbocysteine is usually associated with gastric and intestinal disturbances.
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Rare outbreaks of acute zinc poisoning have been reported. Signs of toxicity seen after taking large doses of zinc (4 to 8 grams) include nausea, vomiting, diarrhea, fever, a metallic taste, and drowsiness (drowsiness).
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See a doctor or contact the poison control center immediately if the patient takes more than the recommended dose.
Overdose of Paracetamol
The overdose symptoms listed below usually occur only 24 hours after taking medicine. An antidote can be given if the ambulance is called soon after taking acetaminophen.
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Abdominal pain, nausea, vomiting.
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liver problems
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Seizures
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Eat and die.
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Death from acetaminophen overdose can take two to four days and is usually caused by liver failure.
Long-term effects
Regular use of acetaminophen may cause the following effects. Discussing the side effects of long-term use with a doctor is best.
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Tired
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Shortness of breath
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Your blue on the fingers and lips.
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Anemia (low number of red blood cells)
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Liver and kidney damage
Drug Interactions:
Drug Interactions Solmux
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Acetohexamide
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Chloramphenicol
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Chlorpropamide
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Disulfiram
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Gliclazide
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Glimepiride
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Glipizide
Drug Interactions Paracetamol
Paracetamol can react unpredictably with some other medicines. It can affect the effectiveness of either drug and increase the risk of side effects.
It can be dangerous to take acetaminophen at the same time as other products containing acetaminophen, including combination products in which acetaminophen is one of the ingredients
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carbamazepine, used to treat epilepsy and certain types of pain
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Cholestyramine: used to reduce itching caused by primary biliary cirrhosis (a type of liver disease).
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Imatinib and busulfan, used to treat some types of cancer
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Ketoconazole, a type of antifungal medicine
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Lixisenatide helps to treat type II diabetes
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Metoclopramide - used to treat symptoms like nausea and vomiting
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Phenobarbital, phenytoin - used to control epileptic seizures
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Warfarin - used to prevent blood clots
There are unknown problems caused by taking acetaminophen with a specific food or consuming alcohol in moderation while taking acetaminophen.
Special attention to be paid?
Special attention of Solmux
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It is best to avoid using carbocysteine during pregnancy, as it can harm the fetus.
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Do not take carbocysteine while lactating.
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If you have a gastric ulcer (peptic ulcer), talk to your doctor before taking this medication.
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Not suitable for children and babies under 2 years old.
If you have the following conditions, you should avoid carbocysteine:
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Allergic to carbocysteine or other ingredients
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Active gastric (peptic) ulcer
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Gastrointestinal bleeding
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Severe renal failure
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Porphyria (a group of rare inherited diseases that primarily affect the skin and nervous system)
Special attention of Paracetamol
Most people are safe to take acetaminophen, including:
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pregnant women
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lactating women
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Children above 2 months of age: Lower doses are recommended for young children (see How to take acetaminophen below).
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If you are still determining whether you can take Paracetamol, read the package leaflet or ask your doctor or pharmacist for advice.
Always seek advice before taking acetaminophen if:
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have liver or kidney problems
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have alcohol problems, such as long-term alcohol abuse.
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they have a very low weight
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you are taking other medicines (see Drug interactions below)
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Do not take if you have ever had an allergic reaction.
Ways of Dispensing
Solmux Dispensing
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capsule
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Syrup
Paracetamol Dispensing
You can buy most types of acetaminophen in supermarkets or drugstores. Some varieties are only made available by showing your prescription.
Acetaminophen is available as:
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pills
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capsules
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liquid, usually for children
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soluble tablets
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suppositories (capsules inserted in the posterior passage)
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an injection is given into a vein, which is normally only used in the hospital.
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acetaminophen is combined with other ingredients in some products, such as cold and flu remedies or combined pain relievers.
Frequently Asked Questions:
1. Does the solmux mucolytic capsule contain aspirin?
Solmux comes with only one ingredient - Carbocisteine, and nothing else.
You can take Aspirin with it.
2. Is solmux safe for diabetic patients?
If you are ingesting Solmux Broncho, that will be safe for diabetic patients. It is because it is sugar-free.
3. Is it okay or safe to use the inhaler Seretide (I do 2 puffs at bedtime) with carbocisteine?
There is no problem in using Seretide along with carbocisteine.
4. If Can Solmux be taken together with Loratadine?
You can give Loratadine (a medicine to treat allergic reactions) with Solmux. There isn’t any problem.
Ensure you don’t have any kidney or liver disease. If yes, avoid this combination of drugs.
5. Is it fine to take solmux with Paracetamol and phenylephrine?
Solmux can also work as a decongestant. However, you can take Solmux with a combination medicine containing Phenylephrine and Paracetamol.
6. How long can someone take Paracetamol?
If you take pain relievers for more than three days, you should consult your pharmacist or family doctor for advice. The prolonged pain you feel may be a sign of something more serious.
7. Is paracetamol an analgesic?
Yes. A pain reliever is a drug that relieves pain.
8. Does Paracetamol contain acetaminophen?
Yes, acetaminophen is just another word for acetaminophen. All acetaminophens are acetaminophen.
9. Is Paracetamol safe for liver and kidney patients?
If you have liver or kidney disease, you should consult a healthcare practitioner before taking any medication. It will ensure that you don’t take unnecessary risks when using acetaminophen.
10. Can Paracetamol affect blood pressure?
No, it does not affect blood pressure or interact with blood pressure medications.
Conclude
Paracetamol (also known as acetaminophen) is a drug commonly used to relieve pain and reduce high temperatures caused by fever. It is frequently used as a first step in treating mild pain. It is available in tablets or syrup.
Acetaminophen takes up to an hour to work. The usual dose of acetaminophen is one or two 500 mg tablets at a time. Trade names are Disprol, Hedex, Medinol, and Panadol.
Solmux is a mucolytic agent for adjunctive treatment of respiratory tract diseases characterized by excessive viscous mucus formation, including chronic obstructive pulmonary disease.