Does Testosterone Expire?

Does testosterone expire? Yes, testosterone can expire after the mentioned expiration date on the box. Usually, testosterone cypionate expires after 36 months of its making. You should avoid injecting expired testosterone, as it can harm your health.

Does Testosterone Expire?

Does Injectable Testosterone Expire?

Name Testosterone Cypionate
Expiration After Opening 28 days
Expiration Without Opening 36 months
Storage Temperature 20°C - 25°C
Half-Life 8 days
Recommendation Once or twice a month.
Most unopened injectable testosterone has a 24–36 month shelf life. After this time, the chemicals inside the vial start to break down, affecting the efficacy, but that doesn’t imply it’s useless. So utilize them all before they expire. Therefore, some testosterone preparations must be used for 18 months.

If you have opened the vial, utilize them within 6–12 months and store them dry and cold. However, don’t put them in the tub. In the summer, avoid hot spots like the rear of your automobile. Therefore, keep it out of the sun. Drawing serum using fresh needles. These steps will help you prolong the expiration date and prevent testosterone degradation.

How To Store Testosterone?

It should be stored at room temperature (15-30°C) and kept away from youngsters. Check the box’s exterior’s expiration date (“EXP”). After the expiration date on the carton and label, do not use your medication. However, keep any drugs away from minors.

Experts say it’s safe to consume expired medicine, even years old. True, a drug’s efficacy decreases over time, but most of the original potency remains even a decade after expiration. Therefore, testosterone cypionate might raise blood pressure and create fluid buildup. Both disorders raise the risk of heart disease.


After the expiration date on the carton and label, do not use testosterone. Keep any drugs away from minors. However, this drug may hurt them. Intramuscular testosterone cypionate has an eight-day half-life.

What Is Testosterone?

Name Testosterone
Chemical formula C19H28O2
Molar mass 288.431 g·mol−1
Melting point 151.0 °C
Biological half-life 2–4 hours
Protein binding 97.0–99.5%
Males’ main sex hormone and anabolic steroid is testosterone. In humans, testosterone promotes secondary sexual traits. Like increased muscle and bone mass and body hair growth and the development of male reproductive organs like the testes and prostate.
Also, testosterone affects both sexes’ health and well-being, including mood, behavior, and osteoporosis prevention. Therefore, insufficient testosterone in males can cause bone loss and weakness.

It works by attaching to and activating the androgen receptor. Therefore, male testicles and, to a lesser extent, female ovaries release testosterone in humans and most other animals. However, males have testosterone levels seven to eight times higher than females.

Males produce around 20 times more testosterone than females due to their higher metabolism. Thus, females are also more sensitive. However, aside from its role as a natural hormone, testosterone is used to treat hypogonadism and chest cancer.

Because testosterone levels decline with age, older men may utilize testosterone to make up for the loss. Additionally, it improves body health and performance, as in sportsmen. “Prohibited at all times,” according to the World Anti-Doping Agency.


Testosterone is an androstane steroid with a ketone and a hydroxyl group at positions three and seventeen. However, it is made from cholesterol and converted to inactive metabolites in the liver.

What is Testosterone cypionate?

Testosterone cypionate, often known as Depo-Testosterone, is an AAS used to treat low testosterone levels in males. It is mostly used in America. Additionally, it is also used to enhance physique and performance. Men’s hormone treatment is utilized in transgender.

In many countries, the drug is a prohibited substance. Therefore non-medical usage is illegal. Testosterone cypionate is a long-lasting prodrug of testosterone. However, it is injected into a muscle or subcutaneously once every one to four weeks. At last, it is one of the most regularly utilized testosterone esters, enanthate, undecanoate, and propionate.

Medical Use Of Testosterone

  • Firstly, testosterone is very useful for male hypogonadism, gender dysphoria, and certain forms of chest cancer.

  • A hormone replacement treatment (HRT) or testosterone replacement therapy (TRT) maintains normal blood testosterone levels. The decline in testosterone production with aging has sparked interest in ART. Therefore, testosterone replacement therapy for older men is controversial.

  • A basic health system requires necessary pharmaceuticals, such as testosterone, listed by the World Health Organization.

  • It is a generic drug. It can be applied to the skin as a cream, injected into a muscle, or swallowed as a tablet.

  • Male testosterone side effects include acne, edema, and chest growth. Chronic liver damage, heart disease, and behavioral problems are serious adverse effects.

  • Women and toddlers exposed may become virilized. Prostate cancer patients should not use the drug. However, it can affect a pregnant or nursing woman.

  • The American College recommendations support the discussion of testosterone therapy in adult males with low testosterone levels and sexual dysfunction.

  • Physicians should investigate intramuscular therapies rather than transdermal treatments due to costs and the identical effectiveness and toxicity of both methods.

  • Treatment with testosterone for purposes other than improving sexual dysfunction is not ideal.

Frequently Asked Questions - FAQs

People asked many questions about the expiry of testosterone. We discussed a few of them below:

:one: Can you use Testosterone Cypionate after its expiration date?

After the first 28 days of use, throw it away. You should not use your medicine after the expiration date written on the carton and label of the drug. Therefore, his drug may be harmful to them.

:two: How long does testosterone stay good?

Firstly, when you have a cypionate testosterone injection, you will notice results in as little as two days. After around 12 days, the effects begin to plateau and can last for up to 21 days in the system.

:three: How long does an opened vial of testosterone last?

Unless the company specifies any different expiration date for that opened vial, the vial should be dated and disposed of within 28 days of opening. It is applicable if you have opened a multi-dose vial.

:four: Is cypionate a steroid?

Testosterone cypionate is an androgen and anabolic steroid (AAS) drug primarily that treats low testosterone levels in males. Additionally, you can also use it to cure various other conditions. However, medical technology is using it to treat transsexual males with hormone therapy.

:five: What does cypionate testosterone do for you?

Synthetic testosterone is famous for treating low testosterone in adult males who have not yet reached puberty. However, as an injection into your buttock muscle, it provides long-lasting results, requiring only one or two treatments each month on average.

:six: How long does cypionate last?

You can find a total of two metabolic pathways in the conversion of testosterone to distinct 17-ketosteroids. According to the manufacturer, you should use testosterone cypionate intramuscularly. It has a half-life of roughly eight days.

:seven: Where do you inject testosterone?

Doctors recommend testosterone injections intramuscularly, which means we should get them directly into muscle tissue. Therefore, the deltoid (upper arm) and the gluteus maximus (lower arm) are two reasonably simple and accessible locations for intramuscular injection.

:eight: Can testosterone cypionate build muscle?

In one study, testosterone injections were related to an increase in lean body mass of 5.7%, an increase in total body strength of 10-13%, and increases in the leg and arm strength. However, treatment with testosterone gel was related to a 1.7% rise in lean body mass and a 2-5% increase in the whole body and arm strength after 12 weeks of treatment.

:nine: Is testosterone cypionate the best?

Specifically for re-establishing normal testosterone levels in males, testosterone cypionate is a very effective hormone replacement treatment that is good for most patients. However, like with any medication, testosterone cypionate has advantages and potential drawbacks, which you should be informed of before using it.

:one: :zero: How often should I inject testosterone cypionate?

Testosterone cypionate is administered by injection into the buttock muscle weekly or biweekly, generally every 1 to 4 weeks. We should not inject this drug into a vein. Therefore, the dosage is decided by your medical condition, testosterone levels in your blood, and reaction to therapy.

:one: :one: Can testosterone cypionate help you gain muscle mass?

In addition to adequate food and exercise, testosterone cypionate has been shown to increase protein synthesis, which aids in muscle growth. ** A healthy dose of TRT will not result in a superhuman muscular gain.

:one: :two: What’s the best testosterone to inject?

100 to 200 mg per week for testosterone enanthate or testosterone cypionate for testosterone treatment is the recommended dose schedule. Weekly injections are preferable because they reduce the variability in serum testosterone levels by injecting more often.

:one: :three: Is testosterone a growth hormone?

Muscle mass gain is a result of testosterone use. Losing weight and gaining more energy are two benefits of a leaner physique. Study after study has shown that therapy can reduce body fat for men with low testosterone while increasing muscular build and strength. Some males saw a shift in lean body mass but not an improvement in strength.

:one: :four: Which is better, testosterone enanthate or cypionate?

In low-T therapy via injections, testosterone enanthate and testosterone cypionate are also excellent possibilities. Enanthate is a miracle drug for maintaining steady blood levels while minimizing adverse effects. Most adverse effects have a brief half-life and may be controlled by varying the dose, frequency, or both.

:one: :five: Where should testosterone be injected?

Intramuscular injections of testosterone are the most common type, administered straight into the muscle. Both the deltoid (the upper arm) and the glut (the gluteus maximus) are very straightforward to access locations for intramuscular injections (upper back portion of the thigh, i.e., the hip cheek).

:orange_book: Conclusion

It is not ideal for taking your testosterone medicine after the expiration date. However, synthetic testosterone is famous for treating low testosterone in adult males who have not yet reached puberty. Therefore, as an injection into your buttock muscle, it provides long-lasting results, requiring only one or two treatments each month on average.

Thus, you should see results within two days, according to standard procedure, when you have a cypionate testosterone injection. After around 12 days, the effects begin to plateau and can last for up to 21 days in the system.

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