NEUPOGEN should be used for a short time until the anti-infective neutrophil count is restored (usually up to 14 days, but may take longer). Stem cell donors are usually treated with NEUPOGEN for 4-7 days.
A transient increase in neutrophil counts is usually seen 1 to 2 days after starting treatment with NEUPOGEN. Therefore, to ensure a sustained therapeutic response, NEUPOGEN is administered daily for up to 2 weeks or until the ANC reaches 10,000 / mm³ after the expected decrease in neutrophils caused by chemotherapy.
If you are taking filgrastim injections during chemotherapy to reduce the risk of infection, shorten the duration of fever or increase the number of white blood cells, you will be given the first dose of the medicine at least 24 hours after receiving a dose of chemotherapy.
Neulasta is a single injection given after each cycle and provides 14 days of coverage. Neupogen can be administered daily for up to 14 days, depending on the type of chemotherapy. The most common side effect in patients is leg pain.
This medicine is usually given at least 24 hours after chemotherapy to stimulate the growth of new healthy white blood cells (white blood cells). Pegfilgrastim is a long-acting form of filgrastim and the manufacturer recommends not taking it within 14 days of chemotherapy.
Ordinary people are at a lifelong risk of developing cancer, including leukemia, lymphoma, or other blood disorders. No long-term risk was identified based on limited long-term data from healthy subjects who received filgrastim.
Tiredness, rash or nosebleed. Reactions at the injection site (redness, swelling, itching, bumps or bruising).
The cost of the Neupogen injectable solution (300 mcg / mL) is approximately $ 3,296 for a 10-milliliter supply, depending on the pharmacy visited.
Take NEUPOGEN out of the refrigerator 30 minutes before use and allow it to reach room temperature before preparing for injection. Discard NEUPOGEN which has been at room temperature for more than 24 hours.
Neupogen® is safe for most adults, but should not be used by people with known hypersensitivity to E. coli proteins, filgrastim, or any of the ingredients in filgrastim. Children and pregnant women should use Neupogen® with caution.
Bone pain due to white blood cell growth factors. We sometimes use loratadine (Claritin) to treat bone pain in patients who develop growth factors in white blood cells. Leg pains reported with these drugs are: Filgrastim (Neupogen) and its biosimilar Filgrastimsndz (Zarxio), 11% to 30%
Filgrastim belongs to a class of medicines called colony stimulating factors because they stimulate the cells in the bone marrow to multiply and form colonies of new cells.
Common side effects of Neupogen are: hyperuricaemia, increased lactate dehydrogenase, increased leukocyte alkaline phosphatase, increased serum alkaline phosphatase, cheese allergy and thrombocytopenia. Other side effects include: arthralgia, headache, muscle aches and itching.
The medicine can be stored out of the refrigerator for up to 24 hours. Throw away any medicines that have been taken out of the refrigerator for more than 24 hours.
Your doctor may prescribe a non-steroidal anti-inflammatory drug (NSAID) such as ibuprofen or naproxen to treat bone pain caused by Neulasta. Neulasta helps the body make more white blood cells by stimulating the immune system, which also produces histamine.
Muscles or joints may become sore or sore two to three days after treatment. It usually goes away after a few days or a week, but for some people it may take a little longer. However, it can be severe and you may need to take mild pain relievers or anti-inflammatory drugs.
Drinking alcohol (in small amounts) has no effect on the safety or benefits of filgrastim. It is best to use contraception while taking filgrastim. Tell your doctor immediately if you or your partner become pregnant.
Filgrastim may be a useful alternative for patients with dengue fever who have low platelet counts. This is the first study to show that taking filgrastim in patients with dengue fever continuously increases platelets and white blood cells within a day and also shortens the duration of the fever.