Coronavirus (COVID-19)

Coronavirus (COVID-19)

(COVID-19) Coronavirus is an infectious disease caused by a newly discovered Coronavirus SARS-CoV-2, which is a respiratory pathogen. First case reported in Wuhan, People’s Republic of China on 31 December 2019.

Classification of Coronavirus (COVID-19)

Coronaviridae is a family of Coronavirus, subfamily Orthocoronavirinae, order Nidovirales, and realm Riboviria, are enveloped viruses with a positive-sense single-stranded RNA genome and a nucleocapsid of helical symmetry. 26 to 32 kilobases is the genome size of Coronavirus, one of the largest among RNA viruses. Club-shaped spikes that project from their surface, which in electron micrographs create an image reminiscent of the solar Corona, from which their name derives.

The life cycle of Coronavirus (COVID-19)

Disease begins when the viral spike protein attaches to its complementary host cell receptor, a protease of the host cell cleaves and activates the receptor-attached spike protein after attachment. Cleavage and activation allows the virus to enter the host cell by endocytosis or direct fusion of the viral envelop with the host membrane it depends on the protease bavailability of host cell.

Symptoms of coronavirus (COVID-19)

Symptoms of COVID-19 are:

  1. Fever
  2. Fatigue
  3. Dry cough
  4. Lost of taste
  5. Sore throat
  6. Diarrhea
  7. Muscles or ■■■■■ pain

COVID‐19 disease symptoms which are severe:

  1. Loss of appetite
  2. Shortness of breath
  3. Pain or pressure in the chest
  4. High temperature

Prevention and Treatment

Prevention

  1. Use soap and water for cleaning hands.
  2. Safe distance maintain from anyone who is coughing or sneezing.
  3. Always should wear a mask when physical distancing is not possible.
  4. Avoid to touch eyes, nose or mouth.
  5. Nose and mouth cover with bent elbow when cough or sneeze.
  6. In the case of fever, cough and difficulty in breathing, seek medical attention.
  7. Staying in home is safe.

Treatment

Specific vaccines or medicines for COVID-19 are not available now. It is under investigation, and will be tested through clinical trials.

Self care

Only treatment is self care. In the case of feeling sick you should rest, drink plenty of fluid, and eat nutritious food. Separate your room from other family members, and use a dedicated bathroom if possible.
Keep a healthy lifestyle at home, a healthy diet, sleep, stay active. Extra love and attention is needed for children from adults during difficult times.
Feeling sad is normal, stressed, or confused during this crisis. When feel overwhelmed talk to a health worker or counsellor. Disinfect and clean regularly touched surfaces.

Medical treatment

Self isolate yourself when you have mild symptoms and are otherwise healthy and contact your medical provider or a COVID-19 information line for advice. Provide medical care if anyone have a fever, a cough, and difficulty breathing.

How dangerous (COVID-19) are:

These three parameters are used to understand in order to assess the magnitude of the risk posed by this disease Coronavirus:

  1. Transmission rate
  2. Case fatality rate
  3. Asymptomatic transmission

Age and conditions of Coronavirus

  1. All ages of people can be infected by the novel coronavirus COVID-19.
  2. People with pre-existing medical conditions (such as asthma, diabetes, heart disease) and people with older ages appear to be more vulnerable to becoming severely ill with the virus.